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Can Creatine Help Support Menstrual Regularity and Women’s Fertility? A Gynaecologist Shares Medical Insight
New Delhi | January 6, 2026
Creatine has long been known as a supplement linked to gym workouts and muscle strength, but in recent years, its role beyond fitness has started to gain attention. In 2026, health experts are increasingly looking at creatine through a wider lens, especially in relation to women’s metabolic health. This shift has led to growing curiosity about whether creatine can play a supportive role in regulating menstrual cycles and supporting fertility.
According to Dr Pankhuri Gautam, Senior Consultant Gynaecologist at Cocoon Hospital, creatine is not just about muscle power. At a cellular level, creatine helps the body produce and recycle adenosine triphosphate, or ATP, which is the main source of energy for all cells. This includes cells involved in reproduction, such as those in the ovaries and the uterine lining.
Dr Gautam explains that the ovaries are among the most energy-demanding organs in a woman’s body. Ovulation, hormone signalling, and preparation of the uterus for pregnancy all rely heavily on a steady supply of cellular energy. When energy levels drop, these processes can slow down. This can sometimes lead to delayed ovulation or irregular menstrual cycles, particularly in women who experience chronic stress, restrictive eating, insulin resistance, or extreme physical fatigue.
She adds that menstrual cycle regularity depends on a delicate balance between the brain, hormones, and ovaries. When the body senses that energy availability is low, it may temporarily shift focus away from reproductive functions to protect basic survival needs. This is often seen in conditions such as hypothalamic dysfunction, stress-related cycle changes, and metabolic disorders like polycystic ovary syndrome, or PCOS.
Creatine, Dr Gautam says, may help by supporting cellular energy efficiency. While it does not directly control hormones or “fix” menstrual cycles, it may help create a healthier metabolic environment that allows the reproductive system to function more smoothly. By helping cells recycle ATP more effectively, creatine may reduce what experts describe as cellular fatigue, especially in energy-demanding tissues like the ovaries.
PCOS, one of the most common causes of irregular periods and fertility concerns, is often linked to insulin resistance and metabolic imbalance. Dr Gautam points to recent research suggesting that creatine supplementation, particularly when paired with resistance exercise, may improve glucose uptake in muscle cells and support better insulin sensitivity. Improved insulin control can positively influence ovarian signalling and ovulation patterns in women with PCOS.
However, she stresses that creatine is not a treatment for PCOS. “It should be seen only as a supportive tool,” she says, “and not as a replacement for medical treatment, lifestyle changes, or proper nutrition.” Women with PCOS should always consult a healthcare provider before adding any supplement to their routine.
When it comes to fertility, Dr Gautam explains that energy plays a key role at every stage, from egg maturation to ovulation and even early embryo development. Healthy mitochondrial function within ovarian cells is essential for these processes. By supporting ATP availability, creatine may contribute to better cellular resilience within reproductive tissues.
That said, she cautions against overestimating its effects. Current scientific evidence does not show that creatine directly improves fertility outcomes or corrects menstrual irregularities. Its role, at best, is supportive and indirect.
For most healthy women, creatine is generally considered safe when taken in standard doses. Still, Dr Gautam advises that women who are pregnant, trying to conceive, or managing hormonal conditions should seek medical advice before using it.
In conclusion, creatine may help support the body’s energy balance, which plays an important role in menstrual health and reproductive function. While it is not a cure or a hormone regulator, it may offer metabolic support when used responsibly alongside a balanced diet, regular exercise, and professional medical guidance.
: Can Creatine Help Support Menstrual Regularity and Women’s Fertility? A Gynaecologist Shares Medical Insight
For years, creatine has been known mainly as a supplement used by gym-goers to build muscle. But in 2026, the conversation around creatine is changing. Health experts are now looking at how it may support women’s overall metabolic health, including menstrual cycle regularity and fertility.
According to Dr Pankhuri Gautam, Senior Consultant Gynaecologist at Cocoon Hospital, creatine plays a role beyond physical fitness. Creatine helps the body produce ATP, which is the main source of energy for all cells. This energy is essential not just for muscles, but also for reproductive organs like the ovaries and uterus.
Dr Gautam explains that the ovaries are highly energy-dependent. Ovulation, hormone signals, and preparation of the uterine lining all require a steady supply of energy. When the body experiences low energy levels due to stress, restrictive diets, insulin resistance, or fatigue, these processes may slow down. This can lead to delayed ovulation or irregular periods.
Menstrual cycle regularity depends on a fine balance between the brain, hormones, and ovaries. When the body senses low energy availability, it may shift focus away from reproduction. Creatine does not directly regulate hormones, but it may help support cellular energy balance, creating a healthier environment for normal ovarian function.
This may be especially relevant for women with PCOS, a condition often linked to insulin resistance and irregular cycles. Some studies suggest creatine, along with strength training, may help improve insulin sensitivity. Better insulin control can support ovulation and cycle regularity, but creatine is not a treatment for PCOS.
When it comes to fertility, Dr Gautam says energy is key for egg development and early embryo growth. Creatine may support cellular health, but current evidence does not show it directly improves fertility. It should be used only as a supportive supplement, with medical advice.
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